Endodontic Flare Up & Management – Extreme pain & swelling during & after root canal treatment(RCT)

Endodontic Flare Up & Management – Extreme pain & swelling during & after root canal treatment(RCT)

Despite our best efforts sometime patient feel extreme pain or swelling during or after root canal treatment commonly known as flare-ups.The clinician should use proper methods and follow appropriate guidelines to prevent these undesirable episodes

 

So, why these flare-up occurs?

They can be due to mechanical, chemical or microbial injury

to the pulp or periapical tissues

let’s first look on Mechanical Injury 

It may occur due to :

Overinstrumentation

it is the most common cause of mid treatment flare-ups

2. Incomplete removal of pulp

tissues can also result in pain

3. Periapical extrusion of debris

can lead to periapical inflammation and then to flare-ups.

Second factor is Chemical Injury:-

Injury to the periapical tissues by :

 

  • Irrigants

  • Periapica medicaments

  • Overextended filling materials

 

Third one is Microbial Induced Injury

It is considered as most significant factor in flare-ups. Bacterial factor combined with above

causes inter appointment pain. So, question arises what factors at microscopic level lead to those changes which causes flare-ups understanding these mechanism is little boring but don’t worry I will guide you through.

let’s start from alteration of Local Adaptation Syndrome

 

In case of chronic pulple diseases, the inflammatory lesion is adapted to irritants but during root canal therapy, a new irritant in the form of irrigation and  filling get introduced in the lesion leading to flare-ups.

 

Next is changes in Periapical Tissue Pressure

 

When pressure below the root canal increases due to excessive puss it creates pain by causing pressure on nerves. Root canal of such teeth when kept open puss comes out but in teeth with less pressure below root bacteria and other irritants get aspirated into the periapical area leading to pain.

 

Next one is Microbial Mechanism in the induction of flare-ups

 

First one is apical extrusion of infected debris:

 

Extrusion of microbes destroy the balance between microbial aggression and defense leading to acute periapical inflammation.

 

 Second is changes in the Endodontic Micro Flora or in Environmental Conditions

 

Incomplete preparation of canal disrupts the balance between the various microbial communities within the root canal system that may favor the overgrowth of dangerous microbes, which can lead to flare-up

 

Next is Secondary Intraradicular Infection

 

It means penetration of the new microbes from the saliva into the root canal system during treatment may lead to a secondary infection and can be a cause of flare up.

 

Next is difficult one Increase of Oxidation-Reduction Potential 

 

Alteration of oxidation reduction potential in the root canal during treatment may favor the overgrowth of dangerous bacteria that resist of a root canal procedure and lead to flare-ups.

 

Other two factors are totally theoretical and I too don’t understand them completely

 

First one is Effect of Chemical Mediators 

 

Chemical mediators can be in 2 form of Cell Mediators or Plasma Mediators

 

Cell Mediators include histamine, serotonin,prostaglandins, plateletactivating factor and lysosomal components which may lead to pain.

 

The Plasma Mediators are present in circulation in inactive form and get activated on coming in contact with

irritants .For example human factor when gets activated after in contact with irritants, produced multiple effects like production of bradykinin and activation of clotting cascade which may cause vascular leakage.

 

Other one is Changes in Cyclic Nucleotide

 

cAMP helps in reducing pain by inhibiting mast cell degranulation where as cGMP increases pain by stimulating mast cell degranulation and during flare-up, there is increased level of cGMP over cAMP concentrations.

 

 let’s move forward from this boring topic to the Management of flare-ups as

 

As the cause of flare-ups are multiple, many treatment options are there for the prevention and relieving of the symptoms during the root canal therapy.

 

Management can be divided into 2 

 

First is Preventive and second is Definitive 

 

In preventive management first step is Proper Diagnosis before starting RCT ,proper diagnosis of the condition should be made so as to prevent incorrect treatment that may lead to pain or swelling then Determine proper working length inaccurate measurement of the working length may lead to under or

over instrumentation and extrusion of debris, irrigants, medicaments or filling material beyond the epex.

And after that most important step is complete debridement thorough cleaning and shaping of the root canal system may decreases the incidence of flare-up. Maintenance of apical patency and crown-down preparation techniques are two important factors in the management of flare-ups. we can also do occlusal

reduction it is a good pain preventive strategy placement of intra canal medicaments in multi vist root canal treatment calcium hydroxide has been recommended as an intracanal medicament for the prevention or treatment of flare-ups. Next is closed dressing leaving a tooth open for drainage is contraindicated as it can cause contamination from the oral cavity and lead to flare-ups. last one is medications antibiotics are not

indicated in the prevention of flare-ups for healthy patient. Antibiotic should be given only in cases of medically compromised patient at high risk analgesic most commonly used drugs include ibuprofen,diclofenac sodium, ketorolac etc.

 

 Now move forward to the other management that is Definitive Treatment

 

First step is drainage through the coronal assess opening

 

The first happened relieving the pain is to establish the drainage through the root canal when it has not been obturated or poorly obturated. Penetration of the apical foramen with the small files should be done to establish the drainage.

 

 Next  method is incision and drainage occasionally abscess present in relation to tooth communicates to vestibule. In these cases flare-ups can be managed through a combination of canal instrumentation and incision and drainage.

 

Proper Instrumentation working length should be re-established apical patency must be obtained and

thorough irrigation should be done.

 

Next is Trephination when drainage through the canal is not possible due to restorative issues or in cases of certain conditions like failing treatment or necessary correction of procedural accident a surgical  trephination can be used as palliative measure. It involves the surgical perforation of the  alveolar cortical plate over the root end to release the accumulated exudates to release pain.

 

However it is not the first line of treatment intracanal medicaments use of corticosteroid antibiotic combination as an intracanal medicament has been recommended to reduce pain especially in case of over

instrumentation.

 

 Analgesics and antibiotics for the most patient the saves are sufficient to control pain however if the pain cannot be controlled with  NSAIDs, opoid analgesics can be used to supplement with NSADIs.

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